UPDATE: 6:44 p.m.
Botetourt Co., VA - The accident earlier on I-81 northbound has been cleared, VDOT reports.
Botetourt Co., VA - A vehicle accident on I-81 northbound has closed the north left lane of traffic and the right shoulder, VDOT says.
The accident is at mile marker 148.5, and a VDOT traffic camera at mile marker 146 shows the northbound traffic at a stand-still.
VDOT says that motorists traveling north can expect major delays.
Traffic backups are between two and three miles.
Stay with ABC 13 for further updates.